This study was carried out to investigate the anatomical features of leaf epidermis of Leea guineense. The leaves were studies using the impression techniques method to obtain epidermal peel. The epidermal peel obtained shows that the stomata distributions in the leaves were more in the adaxial surface than in the abaxial surface in the studies plant. The shapes of epidermis were irregular with undulate anticlinal wall pattern on both surfaces. The numbers of the subsidiary cell in the studied plant were druse oxalate and trichome. The result of the plant studies when combined with the gross morphology of the plant will help in the proper identification of the plant.