The main focus of this research work is to examine the impact of multinational corporations on indigenous industries in Nigeria and economic development of Nigeria. MNC‟s are agent of development in the sense that they constitute the source of capital investment, employment for the people, technological transfer etc. However, many critical of their existence, they are agents of “exploitation”. In this regard, the objective of this work is to ascertain the extent of involvement of multinational corporations in the economic development of Nigeria using indices like employment provision, transfer of technology and to determine the political, socio-economic implications of their existence in Nigeria and also to examine their impact on indigenous industries , in which we will be focusing on key areas of the economy . The materials gathered will be presented and analysed to ascertain if the MNC‟s operations and activities in Nigeria has an impact on the indigenous industries in Nigeria.