EVALUATION OF PHARMACOGNOSTIC PARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTS OF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS

1.1 Introduction

The role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. As example, we have the western medicine with origin in Mesopotamia and Egypt, the Unani (Islamic) and the Ayurvedic (Hindu) system and in Western Asia and the Indian subcontinent and those of the Orient (China, Japan, Tibetetc.). There is a great wealth of knowledge concerning the medicinal,narcotic and other properties of plants that is still transmitted orally from generation to generation by tribal societies, particularly those of the tropical Africa, North and South America and the Pacific countries (Evans, 2009). These are areas containing the world’s greatest number of plant species, not found elsewhere, and with the westernization of so many of the people of these zones there is pressing need to record local knowledge before it is lost forever. In addition, with the extermination of plant species progressing at an alarming rate in certain regions, even before plant have been botanically recorded, much less studied chemically and pharmacologically, the need arises for increased efforts directed towards the conservation of gene pools (Evans, 2009).

Since plant taxa are defined by their morphology (more specifically on the morphology of the flowering parts), identification techniques have relied almost entirely on physical examination of the specimen. However, drying and powdering alters or destroys diagnostic features and the plant parts traded in commerce may not include the parts necessary for establishing botanical identity. Classical description in compendia reflect this approach with physical descriptions that include appearance, color, order, and fracture.