SOCIO CULTURAL IMPLICATIONS OF GENOTYPE TESTS AMONG YOUNG POPULATION IN BUNU KABBA
TABLE OF CONTENTS
Abstract
CHAPTER ONE
INTRODUCTION
Background to study
Statement of the Problem
Objectives of Study
Research question
Hypothesis
SIGNIFICANCE OF THE STUDY
SCOPE OF THE STUDY
CHAPTER TWO
LITERATURE REVIEW
Review of Relevant Theories
Theory of Reasoned Action Core Assumptions and Statements
Health Promotion Model Theoretical Propositions
Attitudes Toward Genetic Testing
CHAPTER THREE
RESEARCH METHODOLOGY
DESCRIPTION OF STUDY AREA
Research Design
METHOD OF DATA COLLECTION
DATA COLLECTION AND ANALYSIS TECHNIQUE
Population and sampling of study
Research Instrument and procedure
Data Analysis
CHAPTER FOUR
RESULT AND DISCUSSIONS
Discussion of findings
CHAPTER FIVE
CONCLUSION AND RECOMMENDATIONS
Conclusion
Recommendation
REFERENCE
Abstract
Genetic diseases are more prevalent in developing countries like Nigeria. So, it is paramount to indulge in genotype tests. Premarital genetic screening could help in its prevention. Awareness and acceptance of pre-marital genetic screening is not well documented in Bunu Kabba, Kogi State. The aim of this study was to determine the socio cultural implications of genotype tests among young population in Bunu Kabba.
CHAPTER ONE
INTRODUCTION
Background to study
Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual’s DNA sequence using biological assays and comparing it to another individual’s sequence or a reference sequence. It reveals the alleles an individual has inherited from their parents. Genetic screening is distinct from screening for other conditions in that it has the potential impact not just on the individuals being screened, but also their family members and society generally.
Genotype testing and screening presents an opportunity for individuals to become informed about their genetic predisposition to diseases, for youths to be informed before going into relationships and for couples to be aware of the possible genetic characteristics of their unborn children. Hence, if one holds the view that one of the reasons for marriage is procreation, then worrying about genetic compatibility and avoiding genetic inheritance of grave consequence becomes something to strongly consider.Themostcommon genetic diseases include sickle cell disease, cystic fibrosis and Tay-Sach’s disease of which sickle cell disease is the commonest. Genotype tests consists of a comprehensive group of tests, especially for those who are planning to get married. According to World Health Organization (WHO),reports have shown that 5% of the world population carries genes responsible for haemoglobinopathies and that Sickle cell anemia is particularly common among people whose ancestors comes from sub-Saharan Africa, India, and Saudi Arabia and Mediterranean countries. Further, over 300,000 babies are born worldwide with sickle cell disease mostly in low and middle income countries, with the majority of these births in Africa. Sickle cell disease is one of the commonest genetic disorder in Nigeria, about 24% of the population are carriers of the mutant gene and prevalence (at birth) is 2%. That is, 15,000 children are born with sickle cell disease genotype annually in Nigeria alone. Sickle cell disease contributes to the equivalence of 5% of under five deaths on the African continent, more than 9% of such deaths in west Africa and up to 16% of under five deaths in individual West Africa countries.
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SOCIO CULTURAL IMPLICATIONS OF GENOTYPE TESTS AMONG YOUNG POPULATION IN BUNU KABBA