The purpose of this study was to investigate teachers’ ICT usage and their job effectiveness in secondary schools in Calabar South Local Government Area, Cross River State. To achieve the purpose of this study, four hypotheses were formulated to direct the study. Literature related to the variables under study was reviewed according to the hypotheses for the study. Survey research design was adopted for this study. A total sample of two hundred (200) respondents were randomly selected for the study. The selection was done through the simple random sampling technique. The questionnaire was used for data collection. Pearson product moment correlation analysis was adopted to test the hypotheses under study. This was because of the nature of the variables involves in the study. The result of the analysis revealed that internet usage, mobile phone usage, computer assisted instruction and hyperlink/multimedia by teachers significantly relate to their job effectiveness in secondary schools. Based on the findings of the study, it was concluded that teachers usage of ICT facilities enhances teaching effectiveness in secondary school. Recommendations and suggestions for further studies were made.